millions treated for hypothyroidism at risk for lung cancer

If people do not wish to find out all they can about their disease that is fine too. Given the clear role that selenium deficiency plays in preventing the conversion of T4 to the far more biologically active form of thyroid hormone known as triiodothyronine (T3), which can cause an elevation of thyroxine-stimulating hormone (TSH), why call a mineral deficiency-induced decrease in T4 a monolithic disease entity such as hypothyroidism? Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism. [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. View the data on our Hypothyroidism Research page. The article also stresses that too many people are being given the diagnosis of either hypo or hyperthyroidism. I have so much to say about this I could write a book. Brit Med J 1978, 1:210212. Forgot account? LifeGivingStore.comRed Light Therapy - Hydrogen Water Generators - Cascara Sagrada - Vitamins, Minerals & Amino Acid Supplements - Cocoa Products - Handcrafted Soaps - Grass Fed Organs & Glandulars - Nano Soma. Considering that the population in Italy is about 60 million people and the sales of LT4 in the country in 2010 were 17.69 million boxes (+ 6% Vs 2009), hypothyroidism, which is the main reason for the prescription, should be a real national concern (almost 0.7 boxes/women/year). Millions of people who were not only wrongly diagnosed with 'cancers' and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. [15] [16]There is also the more logical option of support the bodys thyroid-hormone producing capabilities using the thyroxine precursor L-tyrosine, a basic amino acid with a relatively high margin of safety. Clin Cancer Res 2011, 30:77. Thus, I am monitored carefully. To investigate the magnitude of the possible association between levothyroxine use and cancer risk, this retrospective c I do not believe in random events, of nature or otherwise. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer Correlation is NOT causation. This website is for information purposes only. But what can be done for patients who are at low Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new disease case the patient is converted into a lifelong customer. Levothyroxine and cancer risk study : Hi sorry to - Thyroid UK millions treated for hypothyroidism at risk for lung cancer The great open sky of imagination: for those who u Fermented Foods: Top 8 Reasons to Eat Them. millions treated for hypothyroidism at risk for lung cancer Find how some diseases can be healed with alternative medicine, and share your experience with However, the study looked at the incrase of ALL lung cancers, not SCLC, so that data does not correlate with this study. JavaScript is disabled. May be of interest: Study: Millions Treated for Hypothyroidism At Risk I have always found this condition a riddle. I've been on synthroid for 20+ years, scary. As you know, I appreciate people posting links that help us learn more about lung cancer, too. 1). They found no significant correlation between T4 sales and breast, colorectal and gastriccancers, but did find a significant correlation for lung cancer (p < 0.05) corrected forsmoking and age. [3], An old clinical observation on the relationship between lung cancer and thyroid function reported that patients were characterized by a low concentration of T3 and an increased T4/T3 ratio due to a decrease of 5-monodeiodination (DI). The Remarkable Heart-Friendy Properties of Avocados. millions treated for hypothyroidism at risk for lung cancer I don't think so. 'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low . Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. Hypothyroidism reduces respiratory drive and can cause obstructive sleep apnea or pleural effusion, while hyperthyroidism increases respiratory drive and can cause dyspnea on exertion. Acta Endocrinol 1988, 118:460464. [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. I bet in the previous discussion, if there was one, we would have concluded it was likely that it was because people are generally not put on enough levothyroxine. Considering that the population in Italy is about 60 million people and the sales of LT4 in the country in 2010 were 17.69 million boxes (+ 6% Vs 2009), hypothyroidism, which is the main reason for the prescription, should be a real national concern (almost 0.7 boxes/women/year). This article is copyrighted by GreenMedInfo LLC, 2013, Some features are currently member only features. Curr Opin Endocrinol Diabetes Obes 2010, 17:432436. weight loss, anorexia). " This T4 blocking/endocrine-disrupting property of the synthetic form would also activate a negative feedback loop within the endocrine system, further suppressing remaining thyroid function, and resulting in the atrophy of the compromised thyroid, a iatrogenic 'self-fulfilling prophecy' if you will. UpToDate With the 2013 announcement by a National Cancer Institutecommissioned expert panel that a variety of so-called indolent neoplasms such as ductal carcinoma in situ(DCIS) and high-grade prostatic intraepithelial neoplasia (HGPIN), formerly understood to be forms of breast and prostate cancers, respectively, should be renamed to reflect their intrinsic benignity, a veritable sea change is occurring within the conventional medical establishment. "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)", International Journal of Human Nutrition and Functional Medicine, Osteoporosis Is Scurvy of the Bone, Not Calcium Deficiency, 6 Bodily Tissues That Can Be Regenerated Through Nutrition, 7 Simple Ways to Unclog Your Arteries Naturally, Herbal Cream Clears 87.7% of HPV Cases Naturally, How WHOLE Turmeric Heals the Damaged Brain. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer In my opinion, the science of the study doesn't support the conclusion. Why not simply call it selenium deficiency? Or, if fluoride, mercury, or any number of xenobiotic chemicals in the environment requiring selenium-dependent glutathione-mediated detoxification is causing the low thyroid, why call chemical poisoning hypothyroidism? Whereas a patient who had suboptimal thyroid function, but did not have noticeable symptoms, is suddenly given pharmacological doses of synthetic T4 and suddenly experiences the wide range of acute, adverse health effects associated with a now hyperactive and/or increasingly disrupted thyroid, as a result. Copyright 2008-2023 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM. Kelly Mellott on LinkedIn: Nodify Lung: Nodule Risk Assessment | Biodesix Levothyroxine is a widely prescribed medication for the treatment of an underactive thyroid. Military veterans face increased risk of HPV-related cancer due to low [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. Hypothyroidism results from low levels of thyroid hormone with varied etiology and manifestations. [9] Otto T, Fandrey J: Thyroid hormone induces hypoxia-inducible factor 1 gene expression through thyroid hormone receptor /retinoid x receptor -dependent activation of hepatic leukemia factor. I have sent the link that I read today. (They noted that this age range corresponds to more than 80% of the consumers of the drug and to about 99% of all malignant cancers). [14] K A Woeber. [1] Hercbergs AH, Ashur-Fabian O, Garfield D: Thyroid hormone and cancer: clinical studies of hypothyroidism in oncology. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional. The study included more than 128,000 veterans aged 18 to 26 and found that, just 30.2% of females and 18.7% of males had received HPV vaccination. undefined will no longer be visible to you including posts, replies, and photos. [15] Thanh D Hoang, Cara H Olsen, Vinh Q Mai, Patrick W Clyde, Mohamed K M Shakir. Assessment of oxidative stress and its balance has not been taken into consideration up to now as it should be. It looks at correlations, as if they had any merit on their own. I have been reading Izabella Wentz. I cried with joy when I found out there was something really wrong with me. Keep checking back for the register link to appear. Angiology 2000, 51:S65S68. There are many links attached. The estimated 2.3 million new cases indicate that 1 in every 8 cancers diagnosed in . 1 The number of individuals with thyroid disorders is expected to continue to grow, having reached approximately 750 million globally in 2012. [14] In other words, you can 'normalize' the main clinically measurable parameter associated with 'low thyroid function,' i.e. [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. ", Orsomeone posts something about, say a diet or supplement and them some people think they are something it "Cures lung cancer.". In 2020 alone, there were more than 2.2 million new cases and 1.8 million deaths from lung cancer globally. Perhaps she and I could co-author? Allthewebsites Directory - A niche web directory offering website promotion and other webmaster resources. All the more reason to prescribe T3, I say! [4], More recently DI activity in lung cancer was found to be lower than in peripheral lung tissue.[5]. A couple of caveats to note in this study: The authors found a statistical correlation between the increase in sales of the thyroid medicine Synthroid, and an increase in lung cancer in Italy. I honestly do not know. I wonder if only t3 treatments are preferable than t4 and t3 ? In discussing their findings, the authors noted that they could not exclude the possibility that the condition of hypothyroidism could favor the development of lung cancer. Maybe because they "treat" only with T4 and not T3? Finally, they pointed out that T4, which is a synthetic form of thyroid hormone, might be avoided if T3 or the desiccated pig-derived form known as Armour Thyroid was used to control the oxidative-stress producing hydroperoxides. Tokushima J Exp Med 1991, 38:2535. Increased sensitivity to cold. The authors of the study pointed out that levothyroxine (T4) treatment can lead to medication-induced (iatrogenic) thyroid over-activity (hyperthyroidism) and oxidative stress that can lead to a significant patient discomfort. Very interesting article, thank you for sharing. 'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). Thyroid dysfunction after immune checkpoint inhibitor treatment in a single-center Chinese cohort: a retrospective study Sub-laboratory hypothyroidism and the empirical use of Armour thyroid. J Exp Biol 2010, 213:28992911. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.'. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. If it's high, the test is done again, along with a blood test for the thyroid hormone T-4. Levothyroxine therapy and serum free thyroxine and free triiodothyronine concentrations. A total of 425 inpatients with malignant tumors were treated with ICIs at PUMCH during the study period. florence nightingale concept 2 via de boleto Researchers are currently studying. At GreenMedInfo.com, we have indexed plenty of peer-reviewed research on over 30 natural substances, including nutrients and minerals, which may help to resolve low thyroid function, and conversely, over 30 unnatural substances, e.g. I hope that with increased knowledge we will all find the right road. For a better experience, please enable JavaScript in your browser before proceeding. That's all. Study: Millions Treated for Hypothyroidism At Risk of Lung Cancer. Are you sure you want to block this member? It is worth reading. Different strokes for different folks for sure! Another recently approved drug is tepotinib (Tepmetko). This relatively symptom-free reservoir of 'hypothyroid' cases provides a veritable gold mine of potential office visits, billable services and drug prescriptions. However, they pointed out that the opposite was actually described, and that hypothyroidism reduces the aggressiveness of some cancers because of the presence of thyroid hormone receptors on cancer cells, and spontaneous hypothyroidism may delay onset or reduce aggressiveness of cancers.[1]. But I for one, do appreciate anything that other members forward about potential links, causes, aids to healing, whatever you can them. A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). Hashimoto's disease progresses slowly over the years. This is a horrible disease that ravages the body. Cancer Risk After Radioactive Iodine Treatment for - PubMed Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new 'disease' case the patient is converted into a lifelong customer. This relatively symptom-free reservoir of hypothyroid cases provides a veritable gold mine of potential office visits, billable services and drug prescriptions. [13] Hollowell JG, Staehling NW, Flanders WD. This is a news report of the research, so I can't learn the details of how the science was conducted. Oops, I just saw that I posted the same article. However, that information will still be included in details such as numbers of replies. The American Lung Association connects patients, families, friends and caregivers for support and inspiration as they face lung cancer. PMID: 15253676. [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. Heart problems. Indeed, research indicates that hypothyroid patients treated with T4 replacement, that is sufficient to maintain a normal serum TSH, actually have serum free T4 that is higher than in untreated normal patients and may not result in appropriately normal serum free T3 concentrations. Sayer Ji is the founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, and SteeringCommittee Memberof the Global Non-GMO Foundation. At GreenMedInfo.com, we have indexed plenty of peer-reviewed research on over 30 natural substances, including nutrients and minerals, which may help to resolve low thyroid function, and conversely, over 30 unnatural substances, e.g. [12] Cesarone MR, Belcaro G, Nicolaides AN, Incandela L, De Sanctis MT, Barsotti A: San Valentino epidemiologic project. Monaldi Arch Chest Dis 2003, 59:140145. Asesora y Consultora Web3 para empresas. Once I got on the medication, the symptoms disappeared. Patient characteristics. Sin un requerimiento, el cumplimiento voluntario por parte de tu Proveedor de servicios de Internet, o los registros adicionales de un tercero, la informacin almacenada o recuperada slo para este propsito no se puede utilizar para identificarte. The relationship between levothyroxine use and cancer risk is largely underdetermined. Overtreatment, of course, is the hallmark danger of overdiagnosis. Study: Millions Treated for - Healing Lyme Disease | Facebook For more, visitGreenMedInfo.comand Facebook.com/GreenMedInfo, or sign up forGreenMedInfos free e-Newsletter. Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. [10] Hofer T, Desbaillets I, Hpfl G, Wenger RH, Gassmann M: Characterization of HIFD-1 alpha overexpressing Hela cells and implication for gene therapy. Medical Authoritys System Kills: FDA-Approved Dru Cognitive Impairment, Memory Loss and Alzheimer's Soy Lecithin: How It Negatively Affects Your Healt Cannabis Oil Cures Cancer -Lincoln Horsley's Story New Information Dissolves Illusions About Vaccines Grounding Helps Thin Dangerously Thick Blood and F Tart Cherries Relieve Osteoarthritis Pain, Lieberman's Massive Connections To Big Pharma, Utopian 'Harvest Your Own' Groceries Coming Up. There are several books out there written about the topic. Now, I will bring it to the attention of my Endocrinologist. Currently, the best practical approach is to base treatment decisions on the degree of TSH elevation, thyroid autoimmunity, and associated comorbidities. Even in the mildest form, hypothyroidism affects the heart. As I have lung cancer and just recently was diagnosed hypothyroidI am very interested as to what you have to say about this connection.your personal insight and any books, websites would be appreciated.you may email me if you prefer. [14] In other words, you can normalize the main clinically measurable parameter associated with low thyroid function, i.e. International Journal of Human Nutrition and Functional Medicine, Black Seed May Treat Hypothyroidism (Hashimotos Disease), Clinical Trial Reveals, Wi-Fi Devices Increase Mercury Release From Dental Amalgams, Participating in Drum Circles Improves Health and Quality of Life in Parkinsons Patients (Study), Acupuncture Beats Injected Morphine for Pain: Groundbreaking Study, Mammography Is Harmful and Should Be Abandoned, Scientific Review Concludes, Killer Germs Obliterated by Medicinal Smoke Smudging, Study Reveals, Turmerics Smart Kill Properties Put Chemo & Radiation To Shame, Beet Juice Boosts Cognitive Function In One Dose, 13 Evidence-Based Medicinal Properties of Coconut Oil, Group Drumming Better Than Prozac, Study Suggests, 25 Cancer Stem-Cell Killing Foods That Are Smarter Than Chemo and Radiation, Ibuprofen Can Stop Your Heart 31% Increase in Cardiac Arrest Risk, Conscious Shopping Offering Conscious Products for Conscious People, Uncovering The Truths And Myths About 3 Superstar Herbs, Living Past 100: The Okinawan Diet and Blue Zone Centenarians, Repairs DNA and Rejuvenates Your Cells While You Relax, Why Daily Greens are the Real Fountain of Youth, T4 has been reported as one of the several endogenous factors capable of supporting proliferation of lung cancer cells. ", That study is like a fishing expedition. If you are already a member, please, Levothyroxine and lung cancer in females: the importance of oxidative stress, recent announcement by a National Cancer Institute, T-score based definition of osteoporosis and osteopenia, 30-billion dollar a year market in statin drugs. Ultimately, this latest Italian study is bringing to our attention one of what is likely a wide range of unintended, adverse health effects associated with the overdiagnosis and subsequent overtreatment of hypothyroidism, and the underlying failure of the conventional, largely drug-based paradigm to comprehend the causes and real solutions of disease and human suffering. An Italian study published in the journalReproductive Biology and Endocrinology,titled Levothyroxine and lung cancer in females: the importance of oxidative stress, has raised a concerning possibility: levothyroxine (T4), one of the worlds most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). In comparison, 62.4% of female and 37% of male . MASA Traditional Tortilla Chips by Ancient Crunch, Vitamins, Minerals & Amino Acid Supplements, http://www.greenmedinfo.com/blog/study- ng-cancers, Patients' Perspectives On Refusing Diagnosis Or Treatment For Lung Cancer, Unintended Weight Loss Is The 2nd Highest Risk Factor For Certain Cancers, Stress Causes Genetic Mutations; Cancer Thrives Under Stress, Tetracyclines (and A Few Other Antibiotics) As A Cure For Cancer, Vitamin B May Increase Risk Of Lung Cancer In Men, Study Says, Biggest Study So Far Shows Aspirin Reduces Any Cancer Risk, Methylation Levels Can Predict Breast Cancer Risk, Vitamin A As A Powerful Treatment For Cancer, Screening For Testicular Cancer (a Review), For Many Cancers Early Diagnosis Can Actually Be Deadly, As Altitude Rises, Lung Cancer Rates Fall, The Anti Depression Pills that may Kill Cancer, Holy Grail Blood Test May Detect Cancer Before Tumors Form. It's possible, for instance, that the reason both sales of Synthroid and the incidence of lung cancer increased is due to an environmental condition that affected both the thyroid and the lungs. As a person with Graves Disease, I underwent 6 cycles of radio-ablation using i 131 to 'fry' my thyroid gland as surgery was deemed too risky due to the vascularity and size of my gland. The authors delved deeper into the reason why oxidative stress taking place during T4 treatment is particularly linked to lung cancer only: The hypothesis could be that in lungs the increase of hypoxia-induced factor (HIF-1) which is determined by T4 can make oxygen much more available, increasing locally the oxidative stress together with a dangerous angiogenesis stimulation. Millions Treated for Hypothyroidism at Risk for Lung Cancer I very much appreciate the information you shared. Note: Only a member of this blog may post a comment. hyperthyroidism. The authors delved deeper into the reason why oxidative stress taking place during T4 treatment is particularly linked to lung cancer only: The hypothesis could be that in lungs the increase of hypoxia-induced factor (HIF-1) which is determined by T4 can make oxygen much more available, increasing locally the oxidative stress together with a dangerous angiogenesis stimulation. Millions Treated For Hypothyroidism At Risk For Lung Cancer END TIME NEWS, A CALL FOR REPENTANCE, YESHUA THE ONLY WAY TO HEAVEN. J. Clin. PMID 11836274. Based just on this article, I think the study's conclusion that Synthroid may cause an increase in lung cancer risk is premature. Hypothyroidism - StatPearls - NCBI Bookshelf Treating Elderly for Subclinical Hypothyroidism Can Boost Mortality Rates [3] Faber J, Poulsen S, Iversen P, Kirkegaard C: Thyroid hormone turnover in patients with small cell carcinoma of the lung. So I will leave it as a simple thank you for passing this along. Just for entertainment value take a look at some more dodgy correlations : I rather liked the correlation between consumption of orange marmalade and birth rate - in the years after the second world war if I remember correctly. Biomedicine today is awash in controversy associated with the overdiagnosis and overtreatment of asymptomatic populations. May be of interest: Study: Millions Treated for Hypothyroidism At Risk for, Non-small cell lung cancer - Adenocarcinoma, Non-small cell lung cancer - Squamous cell, Top 5 Questions to Ask Your Lung Cancer Doctor, Patient & Caregiver Network Member Resources, Not A Member Yet? When a high-risk patient presents with one or more lung nodules, the path ahead and next steps seems obvious. [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. Importance: Whether radioactive iodine (RAI) therapy for hyperthyroidism can increase cancer risk remains a controversial issue in medicine and public health. Just another excuse for keeping us on doses that are too low. by D.ap Tue Feb 21, 2017 10:40 am, Powered by phpBB Forum Software phpBB Limited. Thank you for bringing it to our attention. Eventually, the decline in thyroid hormone production can result in any of the following: Fatigue and sluggishness. ', Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer. and our (31) 3351-3382 | 3351-3272 | 3351-3141 | 3351-3371. location of blind frog ranch associe-se. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: "[I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. However, they pointed out that the opposite was recently described, and that "hypothyroidism reduces theaggressiveness of some cancers because of the presence of thyroid hormone receptors oncancer cells, and spontaneous hypothyroidism may delay onset or reduce aggressiveness ofcancers."[1]. hyperthyroidism. In fact, a 2004 study in subjects with normal thyroid function found that administration of tyrosine leads to a significant reduction in serum TSH and improvement in mood in winter compared with placebo, while the combined synthetic T4-T3 supplement leads to a worsening of mood in summer and no improvement in winter, indicating supporting glandular function is superior to 'replacement' therapy, as well as the role seasonality may play in hormone function and hormone treatment interventions. Targeted therapy for lung cancer: Side effects and more I read somewhere about the work done many years ago which was mistakenly read and accepted 28 y/o F Low levels across the board for TSH, T3, and T4, Acid reflux drug linked to more than doubled risk of stomach cancer study, thyroiduk.org - further-reading - thyroid-diagnosis-and-treatment. I discovered this article published in Wakeup World. A study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.'

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