tina huang data scientist

Each bar represents one individual with the ROH grouped in four length categories (grouped by colour). The increasing level of admixture between distinct hunter-gatherer populations from around 8ka onwards indicates an intensified mobility of those forager groups. Tina Huang - Test and Validation Engineer - LinkedIn PLoS Genet. 8). Your email address will not be published. For the placement of individuals onto a Y-chromosomal phylogenetic tree (Extended Data Fig. Its like the different ingredients in your recipe. under exclusive license to Springer Nature Singapore Pte Ltd. 2022 R. Huang et al. Genetics and material culture support repeated expansions into Paleolithic Eurasia from a population hub out of Africa. Bold letters refer to (a) mtDNA and (b) Ychr haplogroups, whose boxes are coloured according to the legend in Extended Data Fig. Itchy Eyes and a Runny Nose? This is first detected in an individual from Gross Fredenwalde in northeastern Germany and reaches around 10% in most European hunter-gatherer individuals thereafter (Extended Data Fig. Nat. 15, 193223 (2005). Similarly, the SMS spam collection data achieves 99.20% for the validation and 99.10% for testing. 14 following. Protoc. (grey) of the f4 values estimated from 5cM-block jackknife analysis. hellotinah Mateja Hajdinjak, Fabrizio Mafessoni, Svante Pbo, D. M. Fernandes, D. Strapagiel, R. Pinhasi, Pavel Flegontov, N. Ezgi Altnk, Stephan Schiffels, Daniel M. Fernandes, Kendra A. Sirak, David Reich, Sandra Oliveira, Kathrin Ngele, Mark Stoneking, Eirini Skourtanioti, Harald Ringbauer, Philipp W. Stockhammer, Vanessa Villalba-Mouco, Marieke S. van de Loosdrecht, Wolfgang Haak, Joseph H. Marcus, Cosimo Posth, John Novembre, Natalija Kashuba, Emrah Krdk, Anders Gtherstrm, Nature The 10 mock interviews provide a great detailed approach to solving any SQL questions. Article Le palolithique suprieur en Italie. Lazaridis, I. et al. Piezonka, H. et al. We further modelled the genetic profile of pre-LGM individuals with qpGraph (Supplementary Information, section10 and Supplementary Figs. 27 and 28). First Name Tina #39. The PCA was calculated with 1379 individuals from 87 western Eurasian modern populations on the 1240k_HO dataset, which was intersected between the 1240k and Human Origins datasets (Supplementary Data 1.K). Curr. This button displays the currently selected search type. Publishers note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. She supports Propel on the business and marketing side. Metadata information of studied individuals. Mathieson, I. et al. The Kostenki (and Sunghir group) ancestry contributed to the previously described Vstonice cluster represented by Gravettian-associated individuals from central-eastern and southern Europe4. Genetically, however, the populations from western and southwestern Europe (today's France and Iberia) differed from contemporaneous populations from central and southern Europe (today's Czech Republic and Italy). Schmitt, T. Molecular biogeography of Europe: Pleistocene cycles and postglacial trends. The dimensions are calculated using newly reported and previously published hunter-gatherer groups or individuals with more than 30,000 SNPs. Shes currently at Microsoft. Data warehousing is a field where you often have to deal with a lot of raw data. Resurrected Supernova Provides Missing-Link, Bald Eagles Aren't Fledging as Many Chicks, Ultracool Dwarf Binary Stars Break Records, Deflecting Asteroids to Protect Planet Earth, Quantum Chemistry: Molecules Caught Tunneling, Shark from Jurassic Period Highly Evolved, 2.9-Million-Year-Old Butchery Site Reopens Case of Who Made First Stone Tools, Gut Microbes Can Boost the Motivation to Exercise, Warmer Climate May Drive Fungi to Be More Dangerous to Our Health, Seawater Split to Produce 'Green' Hydrogen. For consistency with the previously discussed nomenclature, we rename the EHG ancestryas the Sidelkino cluster(hereafter, Sidelkino cluster or ancestry). Then we merged the genotypes from different libraries of the same individual, by randomly picking alleles from available genotype calls, using a custom script. How to Become a Data Scientist at FAANG (Ft. Tina Huang) - Morioh Save my name, email, and website in this browser for the next time I comment. Typically, it calls for a great deal of data heavy-lifting and data visualizations with SQL and Python or R. A number of things can be done with traditional analysis, but it is machine learning that has taken an extremely solid place in product development. Palaeogenomics of Upper Palaeolithic to Neolithic European hunter-gatherers. For ds_halfUDG libraries, we called genotypes on all targeted sites from 2bp-masked bam files; for ds_nonUDG libraries, we called genotypes on transversion sites only; for ss_nonUDG libraries, we called genotypes with single-strand mode, which ignores forward reads at C/T polymorphisms and reverse reads at G/A polymorphisms. Individuals and groups are plotted with the same colours and symbols as in Fig. My experience includes an internship at Goldman Sachs where I did some machine learning work before I took up my current data science job in tech. 6 and Supplementary Fig. Peltzer, A. et al. Sep 2017 - Aug 20181 year. Tina Huang, a data scientist currently working at a FAANG (Facebook, Amazon, Apple, Netflix, and Google Alphabet) company. The more information you have the more data you need to analyze and make your predictions. Soonafter8 ka, Sidelkino ancestry was absent in eastern Spain but it had already reached northern Iberia alongside an increase in Oberkassel ancestry (Fig. Write for us- Weird Science, Energy & Minerals Guest Post. One of the best-known and most liked personalities in the data community, Tina is a successful YouTuber and works with one of the FAANG companies. I'm I've learned SQL before, but I need a refresher. Freshwater radiocarbon reservoir effects at the burial ground of Minino, Northwest Russia. Article Tina Huang - Climate & Environment Knowledge Analyst - LinkedIn We report 47 new radiocarbon dates performed on skeletal elements of 40 individuals by the Curt-Engelhorn-Zentrum Archaeometrie in Mannheim (MAMS, n=29), Center for Isotope Research, University of Groningen (GrA and GrM, n=5), University of Aarhus (AAR, n=3), Beta Analytics (Beta, n=2), Zrich (ETH, n=3), International Chemical Analysis (ICA, n=2), Natural History Museum in Paris (Echo Lab, n=1) and Vilnius (FTMC, n=2) (Supplementary Data 1.A). 14, evac045 (2022). tina huang data scientist The course is well structured and just what one needs before preparing for a data science interview with focus on SQL. Tina Huang hellotinah@gmail.com | 123-456-7890 | 1 BeepbeepBoop St. Philadelphia, PA 19104 EDUCATION AND HONORS University of In addition to her rich experience, including bioinformatics cancer research at OICR, Tina is a . Originally published at https://365datascience.com on October 1, 2020. Gamble, C., Davies, W., Pettitt, P., Hazelwood, L. & Richards, M. The archaeological and genetic foundations of the European population during the Late Glacial: implications for agricultural thinking. To gain an overview of the genomic background of European hunter-gatherers before the LGM, we used multidimensional scaling (MDS) to plot a dissimilarity matrix of pairwise outgroup f3-statistics in the form 1f3(Mbuti; pop1, pop2) (Fig. In other words, youll never have to worry about validity issues or having to re-take the course after a certain amount of time. The MDS analysis showing the genetic affinity among European hunter-gatherers was based on the distance matrix derived from outgroup f3-statistics, in the form 1f3(Mbuti.DG; pop1, pop2) and performed with classical MDS algorithm (cmdscale) implemented in R 3.5.1. A total of 23 patients that had operations in a . The youngest individual carrying large portions of hunter-gatherer ancestry in the analysed dataset is from Ostorf in northern Germany, dated to around 5.2ka (>90% Oberkassel clusterplus Sidelkino-clustercomponents)(Supplementary Data 3.F). F4-statistics further support this view, revealing that Le Piage II is more closely related to the Fournol clusterthan the Vstonice cluster (f4(Mbuti, Le Piage II; Vstonice, Fournol 85)0, Z=6.58). Bioinformatics 29, 16821684 (2013). Citing . The research team describes a large-scale genetic replacement that may have been caused, in part, by climatic changes that forced people to migrate: "At that time, the climate warmed up quickly and considerably and forests spread across the European continent. The levels of contamination from modern human DNA were estimated on the basis of mitochondrial DNA (mtDNA), X chromosome and autosomal DNA, and with a haplotype copying model that is extended here to autosomal data in runs of homozygosity (ROH) (Methods, Supplementary Information, sections2 and 3, Supplementary Figs. Tina Huang, a data scientist currently working at a FAANG (Facebook, Amazon, Apple, Netflix, and Google Alphabet) company. This figure shows (a) the distribution of and interaction between hunter-gatherer genetic ancestries and (b) a simplified schematic representation of major chrono-cultural subdivisions of the European Upper Palaeolithic (green blocks) followed by a grouped Mesolithic to Neolithic block (in gray). Thisancestry profile survived during the Last Glacial Maximum (25,000 to 19,000 years ago) in human populations from southwestern Europe associated with the Solutreanculture, and withthe following Magdalenian culturethat re-expanded northeastward after the Last Glacial Maximum. Dr. Huang taught General Chemistry, Quantitative Analysis, and Instrumental Methods for eight years at . Learn with a sense of purpose. 365 Data Use Cases: Data Science and Product Development with Tina Huang is also supported by the Deutsche Forschungsgemeinschaft (DFG FOR 2237). Natl Acad. I hope youve enjoyed reading this article. Ontario Institute for Cancer Research Toronto, ON. Natural Language Processing (NLP) is another technique that has a well-deserved position in product development. Midzy nami, misiaczkami: Pokaz mody (26) - serial animowany Tina Huang | Chemistry at Illinois Dotted lines delimit geographic regions described in the text. Details of the grouping and ROH segments are provided in Data S3.B. In product development, we do lots of opportunity sizing to decide which features to build and what opportunities to invest in. . Hunter-gatherers carrying an admixed WHG/EHG genetic profile have been sequenced from various regions of northern and eastern Europe, raising the question of how these two types of ancestries formed and interacted with each other through time and space37,38,39,40. Science 360, eaar7711 (2018). Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry. Peresani, M. et al. About the author: Tina Huang is a data scientist at one of the FAANG companies. In addition, our phylogeographic analysis points to northeastern Italy as the possible entry point of the Epigravettian-associated gene pool in the Italian peninsula. Its not just the top 200 that this competition attracts, but anyone interested in data science. Known to have been the coldest phase of the last Ice Age, the LGM is considered to have caused a demographic decline in large parts of Europe10, with populations retracting to southern latitudes as attestedfor exampleby the contemporaneity of the Solutrean culture (2419ka) in the Iberian peninsula and southern France. 6, 16581668 (2022). Most data scientists are used to having to do the dirty work of cleaning and cleansing data. Both of these ancestries carry a genetic component distantly related to the Goyet Q116-1 individual dated to 35ka, with the Iberian individual also showing an affinity to the Villabruna cluster4,14. We visualize the total amount of ROH longer than 4 cM for (a) pre-LGM individuals, (b) Epigravettian- and Magdalenian-associated individuals, (c) individuals carrying high proportions of Sidelkino-related ancestry, and (d) individuals carrying high proportions of Oberkassel-related ancestry. Junior Data Scientist May 2017 - April 2018. Get the most important science stories of the day, free in your inbox. What is surprising is that the Code Cup was so popular that Stanford decided to throw open a Data Science Week in which anyone can submit a code challenge to the top 200 submissions. 21, 199 (2020). Along with pushing for more accessibility, she also creates content around working in the tech industry, the challenges that come with it, and career advice. Nature 528, 499503 (2015). The number of individuals in each group is written to the right of each bar. 4, 11 (2007). These authors contributed equally: Cosimo Posth, He Yu, Archaeo- and Palaeogenetics, Institute for Archaeological Sciences, Department of Geosciences, University of Tbingen, Tbingen, Germany, Senckenberg Centre for Human Evolution and Palaeoenvironment at the University of Tbingen, Tbingen, Germany, Cosimo Posth,Dorothe G. Drucker,Herv Bocherens,Christoph Wiing,Nicholas J. Conard&Katerina Harvati, Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, Cosimo Posth,He Yu,Ayshin Ghalichi,Hlne Rougier,Yilei Huang,Harald Ringbauer,Adam B. Rohrlach,Kathrin Ngele,Vanessa Villalba-Mouco,Rita Radzeviciute,Tiago Ferraz,Alexander Stoessel,Rezeda Tukhbatova,Wolfgang Haak&Johannes Krause, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China, Department of Anthropology, California State University Northridge, Northridge, CA, USA, Universit de Bordeaux, CNRS, MC, PACEA UMR 5199, Pessac, France, Isabelle Crevecoeur,Andr Morala,Stphane Madelaine,Priscilla Bayle,Bruno Maureille,Jean-Guillaume Bordes&Mona Le Luyer, School of Mathematical Sciences, University of Adelaide, Adelaide, South Australia, Australia, Instituto Universitario de Investigacin en Ciencias Ambientales de Aragn, IUCA-Aragosaurus, Zaragoza, Spain, Department of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany, Institute of Zoology and Evolutionary Research, University of Jena, Jena, Germany, Center of Excellence Archaeometry, Kazan Federal University, Kazan, Russia, Department of Biology, University of Florence, Florence, Italy, Martina Lari,Alessandra Modi&Stefania Vai, Estonian Biocentre, Institute of Genomics, University of Tartu, Tartu, Estonia, Tina Saupe,Christiana L. Scheib&Luca Pagani, St Johns College, University of Cambridge, Cambridge, UK, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy, Department of Biology, University of Padova, Padova, Italy, Department of Chemistry G. Ciamician, Alma Mater Studiorum, University of Bologna, Bologna, Italy, Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, UMR 8068 CNRS, TEMPSTechnologie et Ethnologie des Mondes Prhistoriques, Nanterre Cedex, France, Laurent Klaric,Olivier Bignon-Lau,Grgory Debout,Michel Orliac,Pierre Bodu,Bndicte Souffi&Frdrique Valentin, Muse National de Prhistoire, Les Eyzies de Tayac, France, UMR 5140 CNRS, Archologie des Socits Mditerranennes, Universit Paul-Valry, Montpellier, France, UMR 7194, Histoire Naturelle de lHomme Prhistorique (HNHP), Dpartement Homme et Environnement, Musum National dHistoire Naturelle, CNRS, UPVD, Paris, France, Association APRAGE (Approches pluridisciplinaires de recherche archologique du Grand-Est), Besanon, France, Skeletal Biology Research Centre, School of Anthropology and Conservation, University of Kent, Canterbury, UK, Dipartimento di Scienze Fisiche, della Terra e dellAmbiente, U.R. Individuals with at least one library showing Y/Auto ratio > 0.2 were determined as maleindividuals, and with Y/Auto < 0.2 were determined as femaleindividuals4 (Supplementary Fig. USA 110, 1575863 (2013). Natl Acad. The average calibrated date is shown, with pie charts indicating the estimated proportion of ancestry for each group or individual. Other proposed climatic refugia for human survival during this period are the Italian peninsula, the Balkans and the southeastern European Plain, but the actual genetic contribution of populations from these regions to post-LGM Europeans is highly debated11,12,13. Narasimhan, V. M. et al. View Tina Huang's profile on LinkedIn, the world's largest professional community. Libraries were quantified using the IS7 and IS8 primers59 in a quantification assay using a DyNAmo SYBR Green qPCR Kit (Thermo Fisher Scientific) on the LightCycler 480 (Roche). Billed once. Nature 570, 182188 (2019). She then pursued a Masters . Extensive farming in Estonia started through a sex-biased migration from the steppe. We can have either structured data (e.g. Upper Palaeolithic genomes reveal deep roots of modern Eurasians. Ringbauer, H., Novembre, J. A similar pattern is observed through the analysis of ROH segments (Extended Data Fig. 2010, pdb.prot5448 (2010). Tina Huang: Data science, computer science, and career advice expert. In the MDS plot, the Le Piage II individual falls particularly close to individuals belonging to the Fournol cluster, suggesting a local genetic continuity of this ancestry during the LGM (Supplementary Fig. We then attempted to model 250 published and newly reported hunter-gatherers dated to 145ka using qpAdm as a mixture of Oberkassel, Sidelkino, GoyetQ2 ancestries, and an ancestry maximized in Anatolian Neolithic farmers (ANF), as a considerable portion of the sequenced hunter-gatherer genomes date after around 8ka, when ANF ancestry started spreading across Europe. Laplace, G. Essai de Typologie Systmatique (Annali dellUniversit di Ferrara, 1964). Happy International Womens Day! Extended Data Fig. The Kostenki genetic signature (related to the Kostenki 14 genome, and hereafter referred to as the Kostenkicluster or ancestry) contributed to the later Vstonice genetic cluster(hereafter,Vstonice cluster or ancestry), named after the Doln Vstonice site in Czechia4. Tina Huang is a recent graduate of Stanford. 9 Graphical summary depicting the main genetic transformations in post-40 ka hunter-gatherers from Europe. Colour legend is shown in (e). 15-star ratings) or unstructured data (such as social media reviews). . Nakatsuka, N. et al. Ongoing symptoms 3 months after infection by SARS-CoV-2 are well described as long COVID and have become a global health concern [1], [2].Fatigue and dyspnea are the two most common symptoms after infection by SARS-CoV-2 and low physical performance impacting daily activities has been described for up to 6 months after infection [3]. Int. Individuals with libraries showing signs of contamination were further tested using PMD-filtered bam files. Finally, we estimated the genetic diversity of Epigravettian-associated individuals in the dataset by calculating both pairwise mismatch rates (PMR) on pseudo-haploid genotypes and individual heterozygosity levels on pseudo-diploid genotypes (Supplementary Data 3.A). First, we show that individuals associated with the Gravettian culture across Europe were not a biologically homogeneous population. 35, 15471549 (2018). Natl Acad. Bioinformatics 25, 20782079 (2009). Commun. I'm a data scientist and youtuber. Nat. After DNA lysis, a subset of samples was extracted using silica-coated magnetic particles on an automated liquid handling system (Agilent Technologies Bravo NGS Workstation)57. The MySQL engine is also known for being extremely slow compared to others. R Programming in Data Science: High Variety Data SQL Server . Hollywood Heights. In particular, the model achieves 96.21% for the validation and 96.47% for testing using the news aggregator data. Ancient genomes indicate population replacement in Early Neolithic Britain. Taiwan Patent Application M401603, filed 11th April . Tina K. Sorensen | Semantic Scholar Reads with a mapping quality below 30 were then filtered with samtools, and the consensus sequences were generated by Schmutzi69. Otte, M.) 105160 (Errance, 2013). 255, 106796 (2021). Her YouTube channel advises data science jobs, self-study, boosting productivity, resume reviews, etc. Pleistocene mitochondrial genomes suggest a single major dispersal of non-Africans and a Late Glacial Population turnover in Europe. What is a Pie Chart in Data Visualization? Hi friends! The black-outlined diamond marked out in the Gravettian group shows the PMR between the two Gravettian-associated individuals from southern Italy (Paglicci 12 and Ostuni 1). USA 117, 1279112798 (2020). Open access funding provided by Max Planck Society. Designed for aspiring data scientists, data analysts, and BI analysts, this course is the perfect resource for anyone who needs a winning strategy to pass the SQL interview and land their dream job. In practice, we use machine learning in different conjunctures. "With these findings, we can for the first time directly support the hypothesis that during the Last Glacial Maximum people found refuge in the climatically more favourable region of southwestern Europe" says first author Cosimo Posth. The purified products were amplified in multiple 100l reactions using Herculase II Fusion DNA Polymerase (Agilent) following the manufacturers specifications with 0.3M of the IS5/IS6 primers. 359, 318 (2015). Every Thursday, I share insights from books, learning & productivity tips, and a coding challenge. Unlike setting up a Premium subscription to our platform, for which you would be billed monthly or annually, acquiring individual courses requires a one-time payment only. Epoxy Flooring UAE; Floor Coating UAE; Self Leveling Floor Coating; Wood Finishes and Coating; Functional Coatings. Mathieson, I. et al. Connect with them: Email: hellotinah@gmail.com. In the MDS plot (Fig. In this case, the data is being loaded from the MySQL database. Wow! 27, 21852193.e6 (2017). Bioinformatics 20, 289290 (2004). Los Angeles, California, United States. Max Planck Institute for Evolutionary Anthropology. Biol. Subsequently, I worked in bioinformatics for a year and then did my Masters in computer science (MCIT) at the University of Pennsylvania. This, together with the evidence of Villabruna ancestry in El Mirn 19ka, further suggests that this genetic discontinuity could be the result of palaeogeographic and palaeoecological transformations connected to the LGM32, rather than to the BllingAllerd warming period4,15 (14.712.9ka). Hi, my name is Tina and I'm a data scientist at a FAANG company. A dynastic elite in monumental Neolithic society. The f3-statistics were calculated with qp3Pop 435 in ADMIXTOOLS 5.1 package103. SQL for Tech and Data Science Interviews | Udemy Her YouTube channel is dedicated to data and computer science, including how to educate yourself in these topics. Rev. Wren, C. D. & Burke, A. Habitat suitability and the genetic structure of human populations during the Last Glacial Maximum (LGM) in Western Europe. 276, 107319 (2022). 2. Data Science Interviews Course - Special Offer | 365 Data Science The phylogenetic reconstruction of Epigravettian-associated genomes, with Pradis 1 diverging more deeply than all others, indicates that the turnover took place much earlier than 17kathe date of the more derived Tagliente 2 genome. Fu, Q. et al. Previously worked at Goldman Sachs and the Ontario Institute for . In this video, I had the opportunity to talk with Tina Huang, a Data Scientist at one of the FAANG companies. Tina K. Sorensen. The LGM could thus have created a corridor south of the Alps for east-to-west human movements that genetically connected hunter-gatherer populations from the Balkans to Iberia, possibly also via dispersals along existing lower-sea-level coasts32. In product development, 80% of the success of a product is determined by 20% of its features. The Magdalenian culture was widely distributed in southwestern, western and central Europe after the LGM33. Nowadays, we take it for granted that these features exist, but the integrity of those products is, in fact, a labor of love.

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